Covid-19 is a novel, highly contagious but preventable disease caused by a coronavirus (SARS-COV-2) [1]. The Covid-19 pandemic, which was declared a global pandemic by the World Health Organization in March 2020, has impacted the lives of families across the globe including physical, emotional and mental health [2]. Several stressors including prolonged isolation, infection fears and financial loss are known to impact mental health outcomes during the pandemic [3]. Although children appear to be at lower risk for the severe medical complications of Covid-19, the impact of school closures and social isolation have a devastating impact particularly during adolescence, which presents a sensitive period for social interaction [4,5]. During the Covid-19 pandemic, children and adolescents experienced great stress related not only to the fear of getting ill, but also the loss of loved ones, which increased the risk for long-term health outcomes [6]. In this review we will identify the risk factors for, and the current data on the impact of the Covid-19 pandemic on the mental health of children and adolescents.