Soft-tissue lipomas are the most common type of benign mesenchymal tumors and are classified into two types, namely superficial and deep lesions. Superficial, ordinary lipomas occur in the subcutaneous tissues, while deep-seated lipomas occur to the investing fascia. There have been several reports of the superficial lipoma on ultrasonography (US), while a few reports, rare entity, deep-seated lipomas have been studied. In this article, a comparison between superficial and deep-seated lipomas on US features including gray-scale US, color Doppler US and Real-Time Tissue Elastography (RTE) with magnetic resonance image (MRI) appearances was reviewed in detail. The author will suggest that superficial lipoma is usually hyperechoic solid mass without posterior echo enhancement on gray scale US and shows soft nature, having high elasticity on RTE. It is plausible that both superficial and deep-seated lipomas show echogenic lines on grayscale US. The author will suggest that deep-seated lipoma shows moderately soft nature on RTE.