Malaria and Other Infectious Diseases, Suppression
of the Evolution of Drug Resistance

Alan Kleinman

doi:10.26717/BJSTR.2018.12.002219

Review ArticleOpen Access

Malaria and Other Infectious Diseases, Suppression of the Evolution of Drug Resistance

Volume 12 - Issue 2

Alan Kleinman*

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- Primary Care Physician and An Engineer, California, USA

Received: December 05, 2018; Published: December 17, 2018

DOI: 10.26717/BJSTR.2018.12.002219

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Abstract

It is well understood that combination therapy suppresses the evolution of drug resistance. The number of drugs necessary to do this depends on many factors. This paper addresses the key factors in the context of a treatment protocol for malaria which still saw the emergence of resistance despite the use of combination therapy. This paper gives general guidance on the principles of determining the kind and number of selection pressures needed to suppress the evolution of drug resistance.

Keywords :Evolution; Drug Resistance; Suppression; Combination Therapy; Immune Competence; Susceptibility