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Anti-Trib2 Autoantibody in Narcolepsy as A Result of Hypocretin/Orexin Nerve Deciduation

Volume 7 - Issue 3

Susumu Tanaka1,2*, Hisao Yamada1 and Tohru Kodama2

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    • 1Department of Anatomy and Cell Science, Kansai Medical University, Japan
    • 2Sleep Disorders Project, Tokyo Metropolitan Institute of Medical Science, Japan

    *Corresponding author: Susumu Tanaka, PhD, Department of Anatomy and Cell Science, Kansai Medical University, 2-5-1 Shinmachi, Hirakata-City, Osaka 573-1010, Japan

Received: July 20, 2018;   Published: August 01, 2018

DOI: 10.26717/BJSTR.2018.07.001516

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Abstract

Narcolepsy is a disabling disorder characterized by recurrent daytime sleepiness and cataplexy [1]. The 90% to 95% loss of hypocretin (also called orexin) neurons in postmortem brains of narcolepsy is reported [2].

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