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Research ArticleOpen Access

Investigation of Biosynthesized Silver Nano Particles Interaction From Halymenia Porphyroides With The E7 Protein Using Bioinformatics Tool

Volume 1 - Issue 4

Vishnu Kiran M1, Murugesan S1* and Sivamurugan V2

  • Author Information Open or Close
    • 1Division of Algal Biotechnology and Bio-Nanotechnology, Pachaiyappa’s College, India
    • 2PG and Research Department of Chemistry, Pachaiyappa’s College, India

    *Corresponding author: Murugesan S, Division of Algal Biotechnology and Bio-Nanotechnology, PG and Research Department of Botany, Pachaiyappa’s College, Chennai-600030, India

Received: September 02, 2017;   Published: September 15, 2017

DOI: 10.26717/BJSTR.2017.01.000359

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Silver nano particles have known to possess anticancer properties in the early stages of virus proliferation. In the present study biosynthesis of silver nano particles from marine red alga Halymenia porphyroides was synthesized and characterized. Studies on protein disulphide bonds were done using Metal Detector Predicts V2.0 software. All Cys and His residues in amino acid sequences were identified. The study revealed that silver nano particles couple with the sulfhydryl groups led to decrease the disulphide bonds and denatures the E7 protein thus eliminating the possibility of the occurrence of the disease.

Keywords: Bioinformatics; E7 protein; Silver nano particles; Metal binding sites.

Abstract| Introduction| Material and Method| Results and Discussion| Conclusion| References|