*Corresponding author:
Rui-chen Guo, Institute of Clinical Pharmacology, Qilu Hospital of Shandong University, Jinan, ChinaReceived: December 05, 2018; Published: December 12, 2018
DOI: 10.26717/BJSTR.2018.12.002185
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Warfarin and clopidogrel are commonly used anticoagulant and antiplatelet drugs, and their response and/or toxicity were significant influenced by genetic polymorphism of drug metabolizing enzymes transporters and drug targets. Different human populations can differ significantly in genetic allelic frequencies of these enzymes. This paper focuses on genotype and allele frequencies of genes which affect the pharmacokinetic and pharmacodynamic of warfarin or clopidogrel in Han Chinese population detected in our hospital, to provide guidance for the application of pharmacogenomics and clinical pharmacology.
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