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Multiple Sclerosis and the Pathogenicity of Mir-155

Volume 9 - Issue 4

Debajani Mohanty1 and Rajul Rastogi*2

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    • 1 Senior Technical Architect, NIIT Technologies Limited, India
    • 2 Department of Radiodiagnosis, Associate Professor, Teerthanker Mahaveer Medical College & Research Center, India

    *Corresponding author: Rajul Rastogi, Department of Radiodiagnosis, Teerthanker Mahaveer Medical College & Research Center, India

Received: September 30, 2018;   Published: October 09, 2018

DOI: 10.26717/BJSTR.2018.09.001841

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Abstract

Multiple sclerosis (MS) is one of the complex diseases. Genetics, environmental and emotional factors have shown to play essential roles in evoking the disease pathology. More interestingly, epigenetic factors were established as major influencers of the disease severity [1] Of those epigenetic factors; the microRNA (miRNA) plays a fundamental function in MS pathogenicity. MiRNA are small noncoding RNA molecules with a size of approximately 22 nucleotides involved in post-transcriptional regulations of the genes [2-5].

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