*Corresponding author:Miskic B, Faculty of Dental Medicine and Health Osijek, University of Josip Juraj Strossmayer, Croatia
Received: September 18, 2018; Published: September 21, 2018
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For the last two decades the role of Vitamin D3 has been recognized not only as a regulatory component of a bone - kidney metabolism, but also as an important immunomodulator . Low serum levels of vitamin D are detected before an egzacebation in rheumatic diseases: psoriatic arthritis, rheumatoid arthritis and ankylosing spondylitis [2,3].