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Redefining the Role of Cox-2 in Human and Canine Malignancies

Volume 7 - Issue 2

Naresh Kumar Sood1* and Ruhi Sood2

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    • 1Department of Teaching Veterinary Clinical Complex, Guru Angad Dev Veterinary and Animal Sciences University, India
    • 2Department of Veterinary Medicine, Szent István University, Budapest, Hungary

    *Corresponding author: Naresh Kumar Sood, Department of Teaching Veterinary Clinical Complex, Guru Angad Dev Veterinary and Animal Sciences University, India

Received: July 22, 2018;   Published: July 27, 2018

DOI: 10.26717/BJSTR.2018.07.001488

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Abstract

The role of COX enzymes was previously well defined in the inflammation and pain. Recently, studies have shown increased COX-2 expression in malignant tumors of the human and canine patients and its association with multiple events in cancer progression. As of now, it is likely to be a novel target of intervention by combining standard chemotherapy with NSAIDs, especially to delay the progression of cancer.

Abbreviations: Non-Steroidal Anti-Inflammatory Drug (NSAID); Cyclooxygenase (COX)

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