*Corresponding author:Jose Ricardo Kina, Department of Periodontics, São Paulo State University Julio de Mesquita Filho Araçatuba, São Paulo, Brazil
Received: July 09, 2018; Published: July 16, 2018
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Periodontal disease one of the most common and prevalent diseases of the oral cavity has been a challenge in its etiology, diagnosis and treatment. The etiology of periodontal disease is multifactorial, and it is considered that biofilm plays an essential role in its development and evolution .