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ISSN: 2574 -1241
ISSN: 2574 -1241
Received: June 25, 2018; Published: July 03, 2018
DOI: 10.26717/BJSTR.2018.06.001323
The researchers till now have been more focused on the mechanisms of angiogenesis in tumor metastasis. The lack of specific lymphatic markers has been a constraint in establishing the role of lymphatics in tumor metastasis in the past. With the advent of few novel lymphatic markers i.e Podoplanin, Prox 1, LYVE-1, vascular endothelial growth factor receptor-3 (VEGFR-3) and its growth factors VEGF-C and VEGF-D, the research on lymphangiogenesis and lymphatics as a mode of tumor metastasis has picked up. The purpose of this mini-review is to make the researchers aware about the role played by the lymphatics and the process of lymphangiogenessis in mammary cancer metastasis.
Keywords: Lymphangiogenesis; Lymphatic Markers; Mammary Tumor Metastasis
Abstract| Introduction| Lymphangiogenesis and Lymphatic Markers| Conclusion| References|
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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