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Oxovanadium Complexes in Bio Medical Applications

Volume 3 - Issue 3

Jyothy Gopurathinkal Vijayan*

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- Department of Chemistry, Christ University, India
*Corresponding author: Jyothy Gopurathinkal Vijayan, Department of Chemistry, Christ University, Bengaluru-29, India

Received: March 16, 2018; Published: March 29, 2018

DOI: 10.26717/BJSTR.2018.03.000900

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Abstract

Coordination chemistry of Vanadium is largely dependent on the oxidation reduction characteristics of metal center. Vanadium and its oxoions ie, vanadium (IV) and (V) are used as efficient inhibitors of phosphate metabolizing enzymes and also perform as activators. Vanadium oxo-ions are very crucial agents as insulin enhancing agents and anti-tumor agents. These oxo-ions exhibit redox properties under physiological conditions. They are very efficient and act as a cofactor for enzymes in blood sugar metabolism, lipid and cholesterol metabolism and hormone production. Advancements in the medicinal applications of oxovanadium complexes have stimulated their design and synthesis.

Keywords: Insulin Enhancing Agents; Anti-Tumor Agents; Blood sugar metabolism

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