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ISSN: 2574 -1241
ISSN: 2574 -1241
Received: January 08, 2018; Published: January 25, 2018
DOI: 10.26717/BJSTR.2018.02.000693
Nano bio-MOF compounds 3-5 (copper serinate, copper prolinate and copper threoninate) have been evaluated for successful in vitro drugs adsorption of three drugs, named terazosine, telmisartan and glimpiride. Pore sizes and BET surface areas were recorded on N2 adsorption isotherms. In order to elaborate the phenomenon of in vitro drugs adsorption in all these compounds we obtained TGA and PXRD spectra of them. The high performance liquid chromatography (HPLC) was used to monitor the amounts of adsorbed drugs and its slow release from all these compounds.
Keywords: Nano bio-MOFs; Invitro; Drugs adsorption; TGA; PXRD; HPLC
Abbreviations: MOFs: Metal Organic Frameworks; SEM: Scanning Electron Microscopic; HPLC: High Performance Liquid Chromatography; TGA: Thermo Gravimetric Analysis
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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