*Corresponding author:
Gwo-Ping Jong, Division of Internal Cardiology, Chung Shan Medical University Hospital and Chung Shan Medical University, and Basic Science, Central Taiwan University of Science and Technology, Taichung, TaiwanReceived: November 06, 2017; Published: November 14, 2017
DOI: 10.26717/BJSTR.2017.01.000526
To view the Full Article Peer-reviewed Article PDF
Recent epidemiological studies have demonstrated a close association between osteoporotic fractures and common chronic diseases such as chronic obstructive pulmonary disease (COPD), hypertension, chronic kidney disor¬ders, and diabetes. COPD is a chronic inflammatory airway disease, and it well known that osteoporotic fractures are common in patients with COPD. However, reports on the association between COPD and osteoporotic fractures have been inconsistent in the literature. The objective of this review is to discuss the existing literature on the potential association between COPD and osteoporotic fractures in older adults. A PubMed search was conducted to identify studies evaluating the potential association between COPD and osteoporotic fractures in older adults. Overall, the results of these studies showed a non beneficial effect. COPDs have been associated with an increased risk of osteoporotic fractures. Further research is needed on algorithms to identify COPD patients with a high risk of osteoporotic fractures and the beneficial effects of preventing osteoporotic fractures in older patients with COPD.
Keywords: Chronic obstructive pulmonary disease; Osteoporosis fracture; Mechanism