Crystal Structure and Pharmacological Importance of Benzimidazoles and Their Derivatives

Mohamed Ziaulla*

Received: October 02, 2017;   Published: October 13, 2017

DOI: 10.26717/BJSTR.2017.01.000437

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Abstract

Benzimidazoles and their derivatives exhibit a number of important pharmacological properties, such as antihistaminic [1], anti-ulcerative [2], anti allergic [3], and antipyretic [4]. In addition, benzimidazole derivatives are effective against the human cytomegalovirus (HCMV) [5] and are also efficient selective neuropeptide Y Y1 receptor antagonists [6]. We report here in the Crystal structure of 2-(4-(methylthio) phenyl)-1H-benzo[d] imidazole (1) and 2-(4-Methylsulfanylphenyl)-1Hbenzimidazol-3- ium bromide (2).

Introduction| X-ray analysis and Refinement| Acknowledgement| References|