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ISSN: 2574 -1241
ISSN: 2574 -1241
Received: December 05, 2018; Published: December 17, 2018
DOI: 10.26717/BJSTR.2018.12.002219
It is well understood that combination therapy suppresses the evolution of drug resistance. The number of drugs necessary to do this depends on many factors. This paper addresses the key factors in the context of a treatment protocol for malaria which still saw the emergence of resistance despite the use of combination therapy. This paper gives general guidance on the principles of determining the kind and number of selection pressures needed to suppress the evolution of drug resistance.
Keywords :Evolution; Drug Resistance; Suppression; Combination Therapy; Immune Competence; Susceptibility
Background| Results| Discussion| Conclusion| References|
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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