info@biomedres.us   +1 (502) 904-2126   One Westbrook Corporate Center, Suite 300, Westchester, IL 60154, USA   Site Map
ISSN: 2574 -1241

Impact Factor : 0.548

Menu

  Submit Manuscript

Short CommunicationOpen Access

Role of Genetic Factors in the Course of Echinococcosis Disease

Volume 9 - Issue 5

Lukmanova GI1*, Nartailakov MA2 and Lukmanov MI3

  • Author Information Open or Close
    • 1 Professor of the Department of Biology, Bashkir state medical University, Russia
    • 2 Professor, Head of the Department of General Surgery, Bashkir state medical University, Russia
    • 3Assistant of the Department of General surgery, Bashkir state medical university, Russia

      • *Corresponding author: Lukmanova GI, Professor of the Department of Biology of Bashkir state medical University, 450005, Ufa, Lenin 3, Russia

Received:September 28, 2018;   Published: October 11, 2018

DOI: 10.26717/BJSTR.2018.09.001879

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

For several years, we conducted a study of the role of genetic factors in the pathogenesis of echinococcosis among residents of the Republic of Bashkortostan. The associations of polymorphic allele’s genes of cytochrome P-450 (CYP1A1, CYP1A2), glutathione-S-transferases (GSTM, GSTT), cytokines (TNFA), the specificities of Human Leukocyte Antigens (HLA-A, B, DRB1, DQB1) and blood groups AB0 with echinococcosis have been studied. Based on the analysis of the results, it was shown that genetic factors play a role in the invasion of Echinococcus granulosus with genotype G1 (common, domestic sheep).

Keywords : Genetic Factors; Echinococcosis; Albendazole; Cytochrome P450; Polymorphic; Sulfoxide; Enzymes; Catalytic; Patients; Helminthiasis

Abstract | Introduction| References|

Track Your Article

Member In


View More
Newsletter

Archive


News & Events

  • Submissions are now open for NEXT ISSUE (VOLUME 56 – ISSUE 2), APRIL – 2024 Submit Now

Subject Area

e-books

Reprints

Video Articles