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ISSN: 2574 -1241
ISSN: 2574 -1241
Received:September 28, 2018; Published: October 11, 2018
DOI: 10.26717/BJSTR.2018.09.001879
For several years, we conducted a study of the role of genetic factors in the pathogenesis of echinococcosis among residents of the Republic of Bashkortostan. The associations of polymorphic allele’s genes of cytochrome P-450 (CYP1A1, CYP1A2), glutathione-S-transferases (GSTM, GSTT), cytokines (TNFA), the specificities of Human Leukocyte Antigens (HLA-A, B, DRB1, DQB1) and blood groups AB0 with echinococcosis have been studied. Based on the analysis of the results, it was shown that genetic factors play a role in the invasion of Echinococcus granulosus with genotype G1 (common, domestic sheep).
Keywords : Genetic Factors; Echinococcosis; Albendazole; Cytochrome P450; Polymorphic; Sulfoxide; Enzymes; Catalytic; Patients; Helminthiasis
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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