Case ReportOpen Access

PDT, an Adjuvant Therapy to Antibiotic Failure in Streptococcal Tonsillopharyngitis

Volume 6 - Issue 4

**Kate Cristina Blanco*, Natalia Mayumi Inada and Vanderlei Salvador Bagnato**

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- São Carlos Institute of Physics, University of São Paulo, São Carlos-SP, Brazil
*Corresponding author: Cristina Blanco, São Carlos Institute of Physics, University of São Paulo- PO Box 369, 13566-970, São Carlos-SP, Brazil

Received: July 03, 2018; Published: July 10, 2018

DOI: 10.26717/BJSTR.2018.06.001377

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Abstract

In the last decades, the emergence and spread of antimicrobial resistance bacteria has been viewed. Multidrug resistant bacteria are currently considered agents of worldwide emerging diseases and thus an important public health problem. Coordinated efforts to develop new therapeutic strategies are necessary. Photodynamic therapy (PDT) is a therapeutic modality based in photochemical and photophysical processes. PDT has been shown to be effective in bacterial lysis and safe in oral cavity for oral disinfection [1,2]. We report a clinical case of recurrent pharyngotonsillitis (FT) in presence of microorganisms that did not respond to antibiotic treatment. The PDT was applied in three sessions in two steps: application of pharmaceutical formulations containing 0.75 mg/mL curcumin and illumination at 450 nm and 6.57 J/cm2. It was concluded that the PDT may be used as treatment in cases of antibiotic failure. In addition, periodically the PDT may be applied in case of recurrent pharyngitis.

Keywords: Antibiotic Failure;Streptococcal Tonsillopharyngitis;Photodynamic Therapy; Multidrug Resistant Bacteria

Abbreviations: PDT: Photodynamic Therapy; PS: PhotoSensitizer