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ISSN: 2574 -1241
ISSN: 2574 -1241
Received: November 07, 2017; Published: November 29, 2017
DOI: 10.26717/BJSTR.2017.01.000549
Describe method consist of eco-friendly procedure for the preparation of 2,3-dihydroquinazoline-4(1H)-ones from equimolar 2-aminobenzamide and substituted aromatic aldehydes in presence of 20mol% of silica chloride. Green impact of reaction significantly enhanced due to use of water as solvent and recyclable silica-chloride as catalyst. Good to excellent yield of products, simple working strategy and easy purification are the advantage of present methodology
Keywords: Quinazoline; Silica-chloride catalyst; Water mediated; Green methodology
Abstract| Introduction| Experimental| Results and Discussions| Conclusion| References|
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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