Küttner’s Tumour - Chronic Sclerosing Sialadenitis of the Submandibular Gland

CM Bowe¹, C Wan², T Walker³ and S Walsh⁴

Received: November 07, 2017;   Published: November 13, 2017

DOI: 10.26717/BJSTR.2017.01.000525

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Abstract

Chronic sclerosing sialadenitis, originally described by H. Küttner in 1896, is a rare cause of salivary gland enlargement [1]. Its clinical and radiographic presentations can mimic other conditions such as, lymphoma or infectious causes and can only be correctly diagnosed following removal of the gland. This “Küttner’s Tumour” is now classified as an IgG4 related disease, with characteristic dense infiltrate of immunoglobulin (Ig) G4- positive plasma cells. However, the exact aetiology of IgG4 related disease remains unknown with no known role of the IgG4 molecule itself [2]. Other IgG 4 related diseases include Riedel‘s thyroiditis, Mikulicz’s disease and idiopathic retroperitoneal fibrosis [3]. This case demonstrates the diagnostic difficulty of this presentation, with multiple differential diagnoses that cannot be excluded until the final histopathological examination.

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