Research ArticleOpen Access

Study of Chondrosarcoma in Northwest Region of Libya

Volume 1 - Issue 5

**Abdullatef Nureddin*¹ and Moftah Sherad²**

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- ¹Department of Oral Surgery and oral pathology, Tripoli University, Libya
- ²General Pathology Department, Sabrath Tumor Institute, Libya
*Corresponding author: Abdullatef Nureddin, Faculty of Dentistry, Department of Oral Surgery, Oral Medicine and oral pathology, Tripoli University, Libya

Received: September 17, 2017; Published: October 03, 2017

DOI: 10.26717/BJSTR.2017.01.000407

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Abstract

Chondrosarcoma (CS) is a relatively rare malignant tumor of chondroblasts with pure hyaline cartilage differentiation. The neo-plastic cells do not synthesize osteoid, but areas of calcification, ossification and myxoid change may be seen. A total of 14 cases were obtained from two major hospitals in the northwest region of Libya over a period of 6 years. Clinico-pathological data were evaluated including age and gender. The result showed that (CS) was slightly more common in females than in males, male to female ratio was (1.7: 2) with a peak incidence in the second and third decades of life. It is concluded from this study that CS is generally a slightly more common in females than in males and more frequently affected patients in the second and third decades of life. There is no any previous published article regarding this aspect in the northwest region of Libya. Therefore, this paper may will bring forward data for further study of CS in future in Libya.

Keywords: Age; Gender; Libya; CS; Male to Female Ratio

Abbreviations: CS: Chondrosarcoma; IDH1: Isocitrate Dehydrogenase 1; IDH2: Isocitrate Dehydrogenase 2