Oncolytic Virotherapy and Multiple Myeloma

Nahla AM Hamed*

Received: September 08, 2017;   Published: September 25, 2017

DOI: 10.26717/BJSTR.2017.01.000390

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Abstract

OV immunotherapy is an important emerging cancer treatment modality which uses native or genetically modified viruses to destroy cancers. MM is perhaps the ideal malignancy to target using OVs because of the virus permissivity of neoplastic plasma cells and the diseaseassociated immune paresis. OVs have the potential to mediate both tumor debulking and residual disease elimination avoiding the complex and prolonged current therapy for multiple myeloma.

Keywords : OVs: Oncolytic Viruses; MTD: Maximum Tolerated Dose; MM: Multiple Myeloma

Introduction| Oncolytic viruses| Virotherapy of Multiple Myeloma| Conclusion| References|