*Corresponding author:
Hsien-Da Huang, Professor of Bioinformatics, computational biology, and systems Biology College of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, TaiwanReceived: June 18, 2018; Published: June 25, 2018
DOI: 10.26717/BJSTR.2018.06.001292
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Background: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a part of an adaptive immune system in prokaryotes and occurring in diverse forms of bacteria.
Case Presentation: We presented the results of sequence analysis which can help in understanding the presence of CRISPR-mediated antiphage ability in both pathogenic and non-pathogenic strains of Escherichia coli.
Conclusion: Endogenous CRISPR spacers with imperfect matches are the candidates of anti-phage function in genetically distant strains of E. coli.
Keywords: CRISPR/Cas system; Bacteriophage; Escherichia Coli; Spacers
Abbrevations: CRISPR: Clustered Regularly Interspaced Short Palindromic Repeats; CAS: CRISPR-Associated Protein
Abstract| Background| Case Presentation| Discussion| Conclusion| References|