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Review ArticleOpen Access

The Way We Deviate from Baseline

Volume 11 - Issue 2

Yumiko Tozawa*

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    • Department of Nephrology and Endocrinology, Applied Life Sciences, Japan
    • *Corresponding author: Yumiko Tozawa, Department of Nephrology and Endocrinology, Tokyo, Japan

Received: November 14, 2018;   Published: November 26, 2018

DOI: 10.26717/BJSTR.2018.11.002088

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Inflammation can begin acutely or slowly. Inflammation accompanies a number of biological processes in pathology and physiology. The reason why we often conclude based on the rate of initial development of an inflammatory disease that we are soon to be restored to our basal conditions, safe and sound, remains unknown. Here, I present a hypothetical model of an ‘information’-generating system for the body and cell based upon an assumption that our immediate response to external stimuli consists of bodily and cellular responses. Upon the initiation of every stimulus, body and cell must deviate from baseline and then return to baseline. How much the body and cell can deviate from baseline is determined by the capacity of an ‘information’-generating system. The rate of increase in nitric oxide availability in a compartment may be a discriminating factor for the capacity of a cellular ‘information’-generating system.

Introduction| Hypothesis References|