*Corresponding author:Robert A Bara, Faculty of Fisheries and Marine Science, Sam Ratulangi University, Indonesia
Received: September 17, 2018; Published: October 05, 2018
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We performed the study of secondary metabolites from endophytic fungus Aspergillustereus. The fungus was isolated from the ascidian Didemnummolle which grow in the Malalayang waters, North Sulawesi. Chemical investigation of extracts from Biomaltagar found compounds from lactone groups namely Terrein and Butyrolacton VII. The structure of the above compounds was characterized based on spectroscopic data including NMR, UV, IR and MS. Terein and Butyolacton VII showed a narrow spectrum antibacterial activity against Gram positive bacteria Bacillus megaterium DSM32T. So far there was no reports about the antibacterial activity of Butyolacton VII.