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Research ArticleOpen Access

Storage Temperature Influences the Carbamide Peroxide Concentration of at Home Bleaching Agents

Volume 9 - Issue 1

Francine Kerber Vieira Makwitz1, Celso Afonso Klein Junior2*, Eduardo Galia Reston2, Rubem Beraldo dos Santos2, Fernando Freitas Portella3 and Keiichi Hosaka4

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    • 1Department of Operative Dentistry, School of Dentistry, Lutheran University of Brazil, Brazil
    • 2Department of Operative Dentistry, School of Dentistry, Lutheran University, California
    • 3Post-doctoral researcher, School of Dentistry, Lutheran University, Japan
    • 4Assistent professor, Department of Oral Health Science, School of Medical and Dental Science, Japan

    *Corresponding author: Celso Afonso Klein Junior, Department of Operative Dentistry, School of Dentistry, Lutheran University, Brazil

Received: September 10, 2018;   Published: September 18, 2018

DOI: 10.26717/BJSTR.2018.09.001750

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This study aimed to evaluate the influence of storage temperature on the maintenance of bleaching agent concentration and whether concentrations are within the recommendations of the International Standard for products for external tooth bleaching. The samples consisted of ten commercially manufactured and four compounded tooth whitening gels. Hydrogen peroxide and carbamide peroxide bleachin agents at different concentrations were included on analysis. The United States Pharmacopeia and International Standard methods was used to determine the amount of peroxide, in the agents of different brands and concentrations after products storage at 3°C, 20°C and 40°C by 8 days. Analysis was repeated 8 times for each temperature. Differences between means was analyzed by ANOVA and Tukey test at 1% of significance. In general, storage at hot temperatures decreases the peroxide concentration. None of the tested bleaching agents match the labeled peroxide concentration, especially those based on carbamide peroxide from dispensing pharmacy that has differences less than 30% from labeled. These findings indicate that the storage temperature influences the concentration of the peroxides tested.

Keywords: Tooth Bleaching; Peroxides; Hydrogen Peroxide; Drug Stability

Abstract | Introduction | Material and Methods | Results | Discussion | Conclusion | References |