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Mini ReviewOpen Access

Innovation in Nanomedicine - Nanomaterials Camouflaged with Cellular Membrane for Application in Therapies

Volume 8 - Issue 2

J Cancino Bernardi*

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    • Nanomedicine and Nanotoxicology Group, Physics Institute of São, University of São Paulo, Brazil

    *Corresponding author: J Cancino Bernardi, Nanomedicine and Nanotoxicology Group, Physics Institute of São, University of São Paulo, Brazil

Received: August 17, 2018;   Published: August 24, 2018

DOI: 10.26717/BJSTR.2018.08.001634

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Abstract

The application of nanotechnology in the medical field has been growing year by year, reflecting the advances of nanomaterials as theranostic agents for the detection and treatment of diseases, especially in oncology. However, there are several barriers that inhibit the efficiency in the use of these materials for medical applications, for example, opsonization and phagocytosis processes, low biodistribution, and especially, lack of specificity and selectivity. Natural cell membrane nanoparticle coating is one of the newest and most innovative strategies for solving such problems by offering highly selective surfaces that are difficult to achieve using traditional synthetic products. Combined with advances in nanoparticle camouflage are drug delivery and therapies, as photothermal, which makes use of the surface plasmon resonance effect of nanoparticles to generate a rapid localized heating, ideal for favoring the death of cancer cells. In this context, the emphasis of this mini review is presenting some successful research in theranostic nanomaterials camouflaged with cell membranes for therapies and delivery.

Keywords: Nanomedicine; Theranostic; Therapies; Cell membrane; Camouflage; Drug Delivery

Abbreviations: NPs: Nanoparticles; PLGA: Poly Lactic Co Glycolic Acid; PLA: Poly Lactic Acid; Dox: 30 Doxorubicin; HRBC: Human Red Blood Cells; MSC: Mesenchymal Stem Cells; PT: Photothermic Therapy; LSPR: Localized Surface Plasma Resonance; AuNCs: Gold Nanocages

Abstract | Introduction | Discussion | Conclusion | References |