*Corresponding author:Yih-Sharng Chen, Department of Surgery, National Taiwan University College of Medicine and National University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan
Received: June 05, 2018; Published: July 18, 2018
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Purpose: Activated clotting time (ACT) is the mandatory for open heart surgery with cardiopulmonary bypass. Two monitoring systems, Hemochron and i-STAT, were applied for evaluation the difference between these two systems, and their variation.
Methods: Total 36 patients were recruited into the study, 18 for each groups. ACT was checked at 4 time points, before operation (T1), 5 minutes after heparin (T2), hypothermic status (T3), and 5 minutes after protamine reversal (T4). Comparing two groups, the ACT was shorter in i-STAT group at T1, T3, and T4. The ACT in same monitoring system did not show the difference whether live dysfunction or antiplatelet usage. However, the intragroup variation was found much steadier in i-STAT (R2 > 0.9 at 4 timepoints).
Conclusions: Two monitoring ACT system were reliable under cardiopulmonary bypass. Different systems may result results, that operators must realize. The i-STAT ACT may has less variations in different conditions.
Keywords: i-STAT; Hemochron; Cardiopulmonary Bypass
Abbreviations: ACT: Activated Clotting Time; ITC: International Technidyne Corp