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Research ArticleOpen Access

Comparison of Activated Clotting Time Analyzer in Cardiovascular Surgery

Volume 7 - Issue 1

Ya-Chen Wang1, Chen-Hua Wen2, Hsiu-Wen Liang1, Bo-Wei Fong1, Lee-Mei Ponge1, Pei-Hua Lin1, Pin-Hung Hsieh1, Shu-Hui Yang1, Yi-Min Chiang1, Nai-Kwoun Chou1, Chin-Hsieh Wang1, Nai-Hsin Chi1 and Yih-Sharng Chen*1

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    • 1Department of Surgery, Nation Taiwan University Hospital, Taiwan
    • 2Department of Anesthesiology, Nation Taiwan University Hospital, Taiwan

    *Corresponding author: Yih-Sharng Chen, Department of Surgery, National Taiwan University College of Medicine and National University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan

Received: June 05, 2018;   Published: July 18, 2018

DOI: 10.26717/BJSTR.2018.07.001432

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Purpose: Activated clotting time (ACT) is the mandatory for open heart surgery with cardiopulmonary bypass. Two monitoring systems, Hemochron and i-STAT, were applied for evaluation the difference between these two systems, and their variation.

Methods: Total 36 patients were recruited into the study, 18 for each groups. ACT was checked at 4 time points, before operation (T1), 5 minutes after heparin (T2), hypothermic status (T3), and 5 minutes after protamine reversal (T4). Comparing two groups, the ACT was shorter in i-STAT group at T1, T3, and T4. The ACT in same monitoring system did not show the difference whether live dysfunction or antiplatelet usage. However, the intragroup variation was found much steadier in i-STAT (R2 > 0.9 at 4 timepoints).

Conclusions: Two monitoring ACT system were reliable under cardiopulmonary bypass. Different systems may result results, that operators must realize. The i-STAT ACT may has less variations in different conditions.

Keywords: i-STAT; Hemochron; Cardiopulmonary Bypass

Abbreviations: ACT: Activated Clotting Time; ITC: International Technidyne Corp

Abstract | Introduction | Materials and Methods | Results | Discussion | References |