Comparison of Activated Clotting Time Analyzer in Cardiovascular Surgery

Ya-Chen Wang¹, Chen-Hua Wen², Hsiu-Wen Liang¹, Bo-Wei Fong¹, Lee-Mei Ponge¹, Pei-Hua Lin¹, Pin-Hung Hsieh¹, Shu-Hui Yang¹, Yi-Min Chiang¹, Nai-Kwoun Chou¹, Chin-Hsieh Wang¹, Nai-Hsin Chi¹ and Yih-Sharng Chen*¹

Received: June 05, 2018;   Published: July 18, 2018

DOI: 10.26717/BJSTR.2018.07.001432

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

Purpose: Activated clotting time (ACT) is the mandatory for open heart surgery with cardiopulmonary bypass. Two monitoring systems, Hemochron and i-STAT, were applied for evaluation the difference between these two systems, and their variation.

Methods: Total 36 patients were recruited into the study, 18 for each groups. ACT was checked at 4 time points, before operation (T1), 5 minutes after heparin (T2), hypothermic status (T3), and 5 minutes after protamine reversal (T4). Comparing two groups, the ACT was shorter in i-STAT group at T1, T3, and T4. The ACT in same monitoring system did not show the difference whether live dysfunction or antiplatelet usage. However, the intragroup variation was found much steadier in i-STAT (R2 > 0.9 at 4 timepoints).

Conclusions: Two monitoring ACT system were reliable under cardiopulmonary bypass. Different systems may result results, that operators must realize. The i-STAT ACT may has less variations in different conditions.

Keywords: i-STAT; Hemochron; Cardiopulmonary Bypass

Abbreviations: ACT: Activated Clotting Time; ITC: International Technidyne Corp

Abstract | Introduction | Materials and Methods | Results | Discussion | References |