*Corresponding author:
Eduardo Tavares Lima Trajano, Pro-Rectory of Research and Graduate Studies, Professional Master’s Degree in Applied Science in Health, Severino Sombra University, Expedicação Oswaldo de Almeida Ramos Avenue, 280 Centro 27700-000 Vassouras RJ, BrazilReceived: June 26, 2018; Published: July 03, 2018
DOI: 10.26717/BJSTR.2018.06.001330
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Depressive disorders affect approximately 322 million people around the world. People affected by chronic pain are more likely to develop depression. This occur because depression and chronic pain share some neurobiological mechanisms that may overlap. The objective of this study is to perform a review of the common neurobiological and pathophysiological factors between depression and chronic pain.
Keywords: Depression; Pain; Neurotransmitters
Abbrevations: IC: Insular Cortex; CCA: Anterior Cingulate Cortex; HPA: Hypothalamic-Pituitary-Adrenal Axis; CRH: Corticotropin Releasing Hormone; ACTH: Adrenocorticotropic Hormone