*Corresponding author:Toysa T, Licentiate of Medicine, Specialty General Practice, Rehabilitation Hospital Vetrea Terveys Oy, Pohjolankatu 15, FI- 74100 Iisalmi, Finland
Received: June 01, 2018; Published: June 13, 2018
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As CHD, non-CHD (nCHD-the difference between total and CHD mortality), hasits own inter-annual variation and possiblyassociated with dietary factors, e.g. food mineral element contents. Mg is a cofactor in more than 300 enzymatic reactions, so Mg deficiency can be associated with resistance and recovery of a multiplicity of diseases.Antagonism of potassium (K)and Mg is known in plant science. Human nCHD - the mean of female (F) and male (M) nCHD (FM.nCHD) and fertilization rates are based on old data. The dataon Mgrates from liming agents are opened and estimated figures are slightly corrected (to earlier publications). The mineral element ratios were used as 3-year means (3ym), but nCHD as such.Associations of nCHD with [(K/Mg).fm.3ym] are analyzed from periods 1952-99 and 1969-99. In appendix are represented annual relative changes of smoothed (K/Mg).fm and nCHD.
Results: In 1952-1999 (regression by) [(K/Mg).fm.3ym] explained 63.3 % (p < 0.001) and in 1969-99 92.4 % (p < 0.001) of nCHD variation. Regression coefficients were positive. Variation of annual relative changes of smoothed (K/Mg).fm and nCHD were similar and rather simultaneous.
Conclusion: Changes in K and Mg fertilization associated significantly with Finnish non-CHD mortality in 1951-2000. Mechanisms are discussed. Epidemiology of non-CHD needs attention.
Keywords:Non-CHD mortality; Potassium; Magnesium; Balance; Fertilization; Food; Time-related
Abbreviations:3ym - arithmetical 3-year mean; alb - albumin; crea - creatinine ; CHD -age adjusted coronary mortality (I20-I25) of humans, 35-64 yrs; F - female; FM - human; K - potassium; M - male; Mg - magnesium; nCHD (mortality) - difference between total and CHD mortality; S - serum; U -; urineY.i - value of variable Y in year i; Y.(i-1) - variable Y value in year preceding year i, (respectively Y.(i-2)…)