Synthesis and Biological Evaluation of 1-(5-((9H-Carbazol-9-yl) Methyl)-2- Methyl-1,3,4-Oxadiazol-3(2H)-yl)Ethanone

S Muralikrishna*

Received: April 28, 2018;   Published: May 08,2018

DOI: 10.26717/BJSTR.2018.04.001047

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Abstract

SYNTHESIS AND BIOLOGICAL EVALUATION OF 1-(5-((9H-carbazol-9-yl)methyl)-2-methyl-1,3,4-oxadiazol-3(2H)-yl)ethanonering were synthesized by the condensation of 2-(9H-carbazol-9-yl)acetohydrazide with 2-(9H-carbazol-9-yl)-N’-ethylideneacetohydrazide and acetic anhydride. To this reaction was subjected. It forms 2-(1-((4-acetyl-5-methyl-5-(trifluoromthyl)-4,5-dihyro-1,3,4-oxadiazol-2-yl)methyl)-1Hindol -3yl)-3-(p-tolyl)thiazolidin-4-one.The structure of these newly synthesized compounds were characterised by 1H NMR,13CNMR ,Mass ,IR, and elemental analysis.

Keywords: 1, 3, 4oxadiazole; Acetic anhydride; Carboxazole

Abstract| Introduction| Synthesis of 2-(9H-Carbazol-9-yl)-N’-Ethylideneacetohydrazide( 3)| Anti-Bacterial Activity| Antifungal activity| References|