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*Corresponding author:Hui Wang, High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, China
Received: April 26, 2018; Published: May 08,2018
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Stimuli-responsive nanogels have achieved great progress in biomedical fields for clinical diagnosis and therapy due to their porous structures, large surface area, good biocompatibility . Recently, much attention has been focused on the synthesis of stimuli-responsive nanogels with optical maker in polymer network, therefore, realizing the combination of biosensing, bioimaging and controlled drug delivery . Such hybrid nanogels have great potential for disease diagnosis and imaging-guided cancer therapy since the fluorescent imaging not only precisely monitor the change of biosignal in vitro and in vivo, but also identify the location of the tumor region and monitor the treatment progress .