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Review ArticleOpen Access

Osteosarcopenia and Liver Transplantation: More than Sarcopenia and Osteopenia Alone

Volume 3 - Issue 5

Vildan Binay Safer1, Cem Haymana2 and Umut Safer*3

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    • 1Department of Physical Medicine and Rehabilitation, Sultan Abdul hamid Han Training and Research Hospital, Turkey
    • 2Department of Internal Medicine, Gulhane Training and Research Hospital, Turkey
    • 3Department of Paliative Care, Sultan Abdulhamid Han Training and Research Hospital, Turkey

    *Corresponding author: Umut Safer, Department of Paliative Care, Sultan Abdulhamid Han Training and Research Hospital, Palyatif bakim Ünitesi Üsküdar, Istanbul, Turkey, Tel:905062356333; Fax: 902165422010; Email:

Received: March 25, 2018;   Published: April 12, 2018

DOI: 10.26717/BJSTR.2018.03.000954

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Liver transplantation (LT) is critical treatment option in end stage liver disease. After LT osteoporosis and sarcopenia were increasingly reported complication. Both conditions were like two side of coins so current study started to focus on osteo-sarcopeni to better understand complications related these two conditions. However, methodology of studies on sarcopeni in LT limited to create perspective for osteosarcopeni. Aim of present review is focusing on the literature on osteoporoses management in LT, determining potential limitations of sarcopenia studies in LT and highlighting link between osteoporosis and saropenia to create further perspective for studies in LT.

Abbreviations: LT: Liver Transplantation; EWGSOP: European Working Group on Sarcopenia in Older People; IEGS: International Working Group on Sarcopenia; HU: Hounsfield Units

Abstract| Introduction| LT and Osteoporosis| Pathogenesis of Osteoporosis Associated With LT| Prevention and Management of Post-Transplantation Osteoporosis| Evaluation of Sarcopenia in LT Trials| Link between Osteoporosis and Sarcopenias| Counter measures and future directions| References|