Psoriasis is a common immune-mediated chronic inflammatory skin disease. Several cytokines involved in the immunological mechanism
of psoriasis have now been identified. Known cytokines are entangled to form a large signalling pathway and are currently being studied to find
cytokines that play the most important role in pathogenesis. Psoriasis signalling mechanisms have been known through various studies using
cells, mouse models, and psoriasis skin models. The psoriasis skin model is an important tool for psoriasis studies. This review summarizes the
psoriasis skin model currently in use.