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Review ArticleOpen Access

Psoriasis Skin Models as Promising Tools in Psoriasis Research

Volume 2 - Issue 3

InJae Jeong, Hee Jung Lee*

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    • Department of Dermatology, CHA University, Korea

    *Corresponding author: Hee Jung Lee, Department of Dermatology, CHA University, Korea, Tel: 82-31-780-5240; Fax: 82-31-780-5247; Email: derma97@gmail.com

Received: February 01, 2018;   Published: February 13, 2018

DOI: 10.26717/BJSTR.2018.02.000760

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Abstract

Psoriasis is a common immune-mediated chronic inflammatory skin disease. Several cytokines involved in the immunological mechanism of psoriasis have now been identified. Known cytokines are entangled to form a large signalling pathway and are currently being studied to find cytokines that play the most important role in pathogenesis. Psoriasis signalling mechanisms have been known through various studies using cells, mouse models, and psoriasis skin models. The psoriasis skin model is an important tool for psoriasis studies. This review summarizes the psoriasis skin model currently in use.

Keywords: Psoriasis; Skin equivalent; Skin model

Abstract| Introduction| In vitro Models| In Vivo Models| Direct Induced Model| Conclusion| References|