When I was young, I was wondering why the size of chronic
lymphocytic leukemia cells described in Western countries is
always smaller than that of our Japanese patients. Do we have a
different disease? But, I found later that this difference is caused by
the methods how blood smears are dried .
Keywords: How to dry blood smears; Natural-air drying; Forced air drying; Hairy cell leukemia; LGL leukemia
Abbreviations: HCL: Hairy Cell Leukemia; LGL: Large Granular Lymphocytes; LGLL: Large Granular Lymphocyte Leukemia; T-LGLL: T Cell
Large Granular Lymphocyte Leukemia; NK: Natural Killer; FAB: French American British; RBC: Red Blood Cells