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Blood Lymphocyte Morphology: It Depends on How Blood Smears are Dried

Volume 2 - Issue 3

Kazuo Oshimi*

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- Ex-Professor of Department of Hematology, Juntendo University School of Medicine, Japan
*Corresponding author:Kazuo Oshimi, Department of Hematology, Juntendo University School of Medicine, and Kushiro Central Hospital, Japan

Received: January 30, 2018; Published: February 12, 2018

DOI: 10.26717/BJSTR.2018.02.000755

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Abstract

When I was young, I was wondering why the size of chronic lymphocytic leukemia cells described in Western countries is always smaller than that of our Japanese patients. Do we have a different disease? But, I found later that this difference is caused by the methods how blood smears are dried [1].

Keywords: How to dry blood smears; Natural-air drying; Forced air drying; Hairy cell leukemia; LGL leukemia

Abbreviations: HCL: Hairy Cell Leukemia; LGL: Large Granular Lymphocytes; LGLL: Large Granular Lymphocyte Leukemia; T-LGLL: T Cell Large Granular Lymphocyte Leukemia; NK: Natural Killer; FAB: French American British; RBC: Red Blood Cells