Review ArticleOpen Access

Proteomics and Genomics: The Future of Personalized Medicine

Volume 2 - Issue 1

Revati Deshmukh and Priya Nimish Deo*

Author Information Open or Close
- Department of Oral Pathology and Microbiology, Bharati Vidyapeeth Deemed University, India
*Corresponding author: Priya Nimish Deo, Asst Professor, Department of Oral Pathology and Microbiology, Bharati Vidyapeeth Deemed University, Dental College and Hospital, Pune, Maharashtra, India

Received: January 16, 2018; Published: January 22, 2018

DOI: 10.26717/BJSTR.2018.02.000679

Full Text PDF

To view the Full Article Peer-reviewed Article PDF

Abstract

Proteomics and Genomics have opened a new era in the field of research and technology. This has made possible molecular profiling of normal and diseased states. Identification of specific proteins in a particular disease will provide information for drug development which will interfere with the action of those proteins. This will help in establishing targeted therapies. Personalized medicine will provide treatment based on the genetic makeup of an individual and by taking into account the variations noted in a patient. Translation of this research in diagnostics and treatment planning is essential for the benefit of the patient.

Abbreviations: HNSCC: Head and Neck Squamous Cell Carcinoma; LOH: Loss of Heterozygosity ; CYP: Cytochrome P450; GSTM: Glutathione -S-Transferase Genes; UGT: UDP-glucuronosyl transferase; MMP: Matrix Metalloproteinases; Ig: Immunoglobulins; TNF: Tumor Necrosis Factor; CHS: Chediak- Higashi Syndrome; SNP: Single Nucleotide Polymorphism ; 2D PAGE: 2- Dimensional Polyacrylamide Gel Electrophoresis