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Research ArticleOpen Access

Prognosis Comparison Molecular Subtype Breast Cancer between Young and Adult Women at General Hospital Dr. M Djamil Padang

Volume 1 - Issue 6

Azamris*1, Irwan1 and Hafni Bachtiar2

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    • 1Surgery Department of Medical Faculty, University of Andalas/General Hospital, Indonesia
    • 2Public Health Department of Medical Faculty University of Andalas, Indonesia

    *Corresponding author: Azamris, Cibinong Science Centre, Jl Raya Bogor Km. 46, Cibinong 16911, Indonesia

Received: October 30, 2017;   Published: November 08, 2017

DOI: 10.26717/BJSTR.2017.01.000508

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Breast cancer is a heterogenic disease with various biologic profiles and clinical prognosis. A research in Netherland by Esther, et al 2013, showed that molecular subtypes of breast cancer have different distribution and prognostic between young and adult, but there is no local and national data.A Comparative research with cross sectional design was Held in January-April 2015 with 96 samples of breast cancer women with age < 40 years old and > 40 years old, recorded in medical records and breast cancer registrated from 2012-2014. Young women Breast cancer at General Hospital Dr. M. Djamil Padang for 3 years (2012-2014) are 27.1% and the adult are 72.9%. In bivariate analysis, there are no relationship between characteristics of tumor with recurrent and death event while in the adult women breast cancer, tumor size and metastases have relation with recurrent and death event that are statistically significant. There are different characteristics and description of molecular subtype breast cancer between young and adult women, young ages are tend to have big tumor, lymph node positive, lympovascular invasion, high grade tumor, proliferation index Ki67 high and negative hormone receptor. There are different tendency of prognosis women breast cancer between young and adult based on molecular subtype but statistically, the relationship is not significant.

Keywords: Age; Breast Cancer Molecular Subtype; Prognosis

Abstract| Introduction| Material and Method| Results| Discussions| References|