Pinning Down HELLP: A Review
Hafizur Rahman*
DOI: 10.26717/BJSTR.2017.01.000267
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- Institutional affiliations of author, Professor of Obstetrics and Gynecology, Sikkim Manipal Institute of Medical Sciences, India
Corresponding author:
Hafizur Rahman, Professor of Obstetrics & Gynecology, Sikkim Manipal Institute of Medical Sciences, 5th Mile, Tadong, Gangtok,
Sikkim-737102, India
Received: August 04, 2017; Published: August 10, 2017
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Abstract
Preeclampsia and HELLP syndrome, both disorders unique to pregnancy, remain a major cause of maternal and neonatal mortality and
morbidity worldwide. It is the most common medical disorder complicating pregnancy. In both of these disorders, the liver is a major target
with often devastating consequences. The pathogenesis of hepatic damage in cases of severe preeclampsia and HELLP syndrome is not well
understood. Diagnosis of HELLP syndrome is heavily relied upon laboratory investigation. In the management, first priority is to assess and
stabilize the maternal condition, particularly coagulation abnormalities followed by evaluation of fetal well‑being and finally, a decision must be
made as to whether or not immediate delivery is indicated. Women with a prior history of HELLP syndrome carry an increased risk of at least
20% (range 16%-52%) risk of recurrence of some form of hypertension, so future pregnancy counseling and follow up is essential.
|Abstract|
|Introduction|
|Pathogenesis|
|Clinical Presentations|
|Diagnosis and Classification|
|Maternal and perinatal morbidity and mortality|
|Management|
|Patient Counseling: Future Pregnancy|
|References|
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ISSN: 2574 -1241
