Pulsed EMF Device Counters Inflammation, Cardio Stress, Cartilage Loss, and Promotes Tissue Repair Volume 63- Issue 3

Thomas F Valone*

• Integrity Research Institute, USA

Received: September 12, 2025; Published: September 25, 2025

*Corresponding author: Thomas F Valone, Integrity Research Institute, 5020 Sunnyside Ave., Suite 209 Beltsville MD 20705, USA

DOI: 10.26717/BJSTR.2025.63.009881

Abstract PDF

A biomagnetic device meets the specified features of publicized NASA research, providing tissue repair, cardioprotection, and cartilage regeneration noninvasively. In addition, by activating the Heat Shock Protein (HSP 70) locally, it has been shown to provide rapid pain relief from inflammation caused by impact trauma, tissue injuries, organ malfunction, some diseases, and occasionally, even some chronic conditions.

Abbreviations: PEMF: Pulsed Electromagnetic Field; IRI: Integrity Research Institute; HSP: Heat Shock Protein; TNF: Tumor Necrosis Factor

It has been proposed that future widespread use of energy medicine will save health care [1]. An electrotherapeutic product called the EM Pulser Model 78 is a portable, battery-powered pulsed electromagnetic field (PEMF) therapy device designed to relieve pain, accelerate healing, and support cardiovascular health. It delivers low-frequency magnetic pulses at the Earth’s natural Schumann frequency of 7.8 Hz, a rate clinically validated by NASA scientists for its ability to promote tissue repair [2] and cartilage regeneration [3]. The EM Pulser 78 from Integrity Research Institute (IRI), designed by Glen Gordon, a medical doctor following a four-year NASA PEMF Study [4], activates the heat shock protein (HSP 70) within just 10 minutes, offering a targeted, non-invasive approach to reducing, and if used quickly, completely stopping the inflammatory response and speeding recovery (Figure 1).

Figure 1

Heat Shock Protein (HSP70)

Heat Shock Protein is a vital protein cited by Glen Gordon, MD as being drawn to an area of the body activated by nanosecond pulse rise time PEMF, as found in the four-year NASA Study noted previously. It is amazing in that HSP seems to have intelligent intervention capability that overrides less desirable response functions of the human body, especially in arresting the inflammation that immediately accompanies trauma in any form. It originally was identified by its ability to protect cells in the case of rapidly increasing heat exposure. For example, one source emphasized, “Animals with higher heat-shock protein levels can thrive in triple-digit temperatures.” Furthermore, we find that “HSP70 proteins can act to protect cells from thermal or oxidative stress.” Oxidative stress is a fancy way of describing free radical damage. And free radicals are formed daily in the body, from a wide range of sources, including chlorinated municipal tap water flowing directly onto the warm naked human skin in a shower without a good shower filter that removes chlorine, since chlorine dissociates at body temperature into monochlorine radicals, each of which replicate other free radicals about 10,000 times [5]. HSP70 is also regarded as a “chaperone” protein, which also helps protect against “stress-induced apoptosis” which is self-destructive cell death (Mosser, 2000).

Members of the HSP70 family are very strongly upregulated by heat stress and toxic chemicals where upregulate means to support, catalyze, and encourage biophysically and biochemically. HSP70 also aids in transmembrane transport of proteins. HSP70 seems to be able to participate in disposal of damaged or defective proteins. Finally, in addition to improving overall protein integrity, HSP70 directly inhibits apoptosis, revitalizing cells. One recommended reference paperback is the Malyshev book pictured here on the effect of HSP70 on tumors and immunity. Other references listed in the Bibliography include an article on inhibiting motor and sensory neuron degeneration (which means that stimulating HSP70 to a site may reverse nerve damage perhaps. (Tidwell, Houenou, & Tytell, 2004). Another one talks about preventing skeletal muscle atrophy, which we all need as we get older (Senf, Dodd, McClung, & Judge, 2008). A third citation indicates how HSP70 can have beneficial effects on Parkinson disease, Alzheimer’s, cerebral ischemic injury, and even in the immune response to multiple sclerosis (Turturici, Sconzo, & Geraci, 2011). One more interestingly offers protection against tumor necrosis factor (TNF) which can be lethal. The authors used heat shock (HS) to attract HSP70 to the organ being tested for the antitumor protocol (Molle, et al., 2002) Hopefully, this information will help the reader appreciate the wide range of HSP70 effects and benefits. In addition, the subsequent articles by Dr. Gordon in this manual shows that HSP70 may also be stimulated and attracted toward a particular site in the body to benefit and repair cellular tissues, primarily in that area targeted by nanosecond rise time PEMF.

Summary of Heat Shock Proteins’ Health Benefits

1. Heat Shock Proteins Act as Chaperones
2. HSPs Prevent Cell Death
3. HSPs Play a Role in Immune Response
4. HSPs Make Sure Steroid Hormone Receptors Function
5. HSPs Protect the Heart
6. Heat Shock Proteins May Help Prevent Diabetes [6]

Foods and Supplements That Increase HSP70

• Broccoli sprouts/Sulforaphane (Zhang, 2011)
• Extra Virgin Olive Oil (Menendez, 2013)
• Zinc (Putics, 2008)
• Curcumin (Shen, 2007)
• Resveratrol (Han, 2012)
• Blueberry (Galli, 2005)
• Graviola (Moghadamtousi, 2015)
• Lavender Essential Oil (Huang, 2012)

Bio-Magnetic Pulsed Therapy

“Magnetic field therapy is not just a futuristic concept—it’s a proven method for reducing pain and promoting healing at a cellular level,” said a company spokesperson, Dr. Jacqueline Panting, who is a naturopath. She further explained, “The EM Pulser Model 78 brings this technology to anyone looking for a safe, non-invasive way to manage pain and recover from injuries. It is used by our client physicians even in the ER.” Designed for convenience, the device weighs just two ounces and features a rechargeable lithium-ion battery. The EM Pulser also has an AC recharger, a soft blue rubber boot including a belt loop for the free double-sided Velcro strap, and a magnetic compass to confirm the strength and oscillation of the pulsed magnetic field. The EM Pulser Model 78 can be used to treat a range of conditions, including sprains, fractures, back pain, sciatica, post-surgical healing, migraines, and gynecologic pain. It also offers cardioprotective benefits by matching the earth’s Schumann Resonance frequency of 7.8 Hz, as shown in a 2019 study published in Nature Scientific Reports [7]. The Schumann resonances (or frequencies) are nearly standing electromagnetic waves that exist in the cavity (or space) between the Earth’s surface and the ionosphere. In 1952, German physicist Professor Winfried Otto Schumann of the Technical University of Munich started exploring whether the Earth itself has a frequency – a pulse.

His idea about this frequency stemmed from his understanding that when a sphere exists inside another sphere, electrical tension is created. Since the negatively charged Earth exists inside the positively charged ionosphere, there must be tension between the two, which gives the Earth a specific frequency. After a series of calculations, he deduced a frequency he believed was the pulse of the Earth-ionosphere space. Two years later, in 1954, Schumann and Herbert König reported consistent and predictable frequencies in the atmosphere that occurred in the space between the Earth’s surface and the ionosphere. Although several frequencies occur between 6 and 50 cycles per second, the fundamental frequency they identified was 7.83 Hz. For enhanced functionality, the EM Pulser device can be paired with optional accessories, such as the near-infrared red light LED probe for deep tissue penetration and improved vision for a three-minute exposure on a weekly basis [8]. The complete combination pack also includes a UV probe for disinfection, a separate magnetic coil probe, and the PulsePad for broader coverage on tender areas. These addons are available separately or as part of the full package for a reasonable fee. A recent customer shared, “I love this new model 78. I just had to buy a second one, so I am never without it. It has helped me to sleep soundly, and I feel more alert. I am 78 years old and have lots of aches and pains, and this device is helping a lot. So grateful for this product, great price too.” Interested parties can find additional information by visiting http://www.BioenergyDevice.org. The Scientific Reports article also explains the benefit (cardioprotection from stress) from using a device with the same pulsed waveform and pulse rate (7.8 Hz) as the EM Pulser (Figure 2).

Figure 2

NASA Confirms Cartilage Restoration with High Slew Rate PEMF

NASA has also found more benefits from Pulsed ElectroMagnetic Field (PEMF) devices that have major implications for restoring health and well-being for astronauts in space. At least two of their recent patented discoveries explicitly use a 9-volt device just like the EM Pulser 78 electrotherapy PEMF device that IRI has been manufacturing and marketing to over one thousand people already. It serves as an endorsement from NASA for their studies on cartilage and tissue repair from such a product like IRI which has the same specifications such as waveform, wrap-around pad, high slew rate and pulse rate. NASA Tech Briefs specifically highlight the “device that can alleviate cartilage degradation in synovial joints by promoting the growth of new cartilage.” Furthermore, their conclusion is even broader for possible treatment areas: Results show that variation of waveform used in PEMF therapies, independent of flux intensity, influences genetic regulation of HCH from patients with early-stage osteoarthritis. The device has potential to be used in the treatment of cartilage degenerative joint disorders in patients resulting from rheumatism, trauma, or surgery.Scientists at IRI realized that our mentor and inventor of the EMpulse, Glen Gordon MD, obtained his original design for his PEMF device from a NASA study [9], finding that a fast rise time of the pulse stimulates the heat shock protein (HSP 70) which helps heal tissue trauma quickly and also counters inflammation more effectively than icepacks or aspirin.

Therefore, IRI followed his design years ago and perfected the EM Pulser 78 with a 7.8 Hertz pulse rate that Dr. Gordon recommended, based on the earth’s Schumann Resonance and the brain’s alpha rhythm. It also has a nanosecond rise time as well, which has satisfied over 1000 clients who use the affordable electrotherapeutic product www.BioenergyDevice.org. Since NASA found that a wrap-around pad was also helpful for joints, to stimulate new cartilage growth, IRI produced an attachment called the “PulsePad” (see photo on left) years ago, which is a 4” x 6” pad specially designed with a flexible, pancake coil to produce the same 7.8 Hz magnetic PEMF in the pad, similar to but smaller than NASA’s wrap-around pad, and can be placed under clothing, powered by the EM Pulser secured to one’s belt with convenient, built-in belt loops (Figure 3).

Figure 3

NASA Finds Tissue Repair is Enhanced with PEMF

NASA has also presented a patent collection for a pancake coil pad, with a square wave PEMF design and this time with additional details such as being driven by a 9 V battery that can be wrapped around an area of the body that needs healing. Released in 2023, it comes years after IRI has been selling exactly the same type of product with our EM Pulser 78 combined with EM PulsePad or an OsteoPad accessory pad. However, NASA has a better technical name for this invention. Therefore, people can either apply to license the NASA invention or visit the IRI dedicated webpage www.BioenergyDevice.org and try one for themselves today, with a 30-day return policy, which also includes the other NASA-discovered benefit of cartilage regeneration and HSP70 stimulation. A snapshot of NASA’s promotion through its Tech Briefs is also shown here [10].

Possible Long Lasting Memory Improvement with PEMF

Another development that seems to endorse the EM Pulser design is the recent Grover et al. article reported in Nature Neuroscience. They found in their study that a theta modulation frequency of 4 Hz can be utilized for stimulating and improving working memory (WM). It turns out that this frequency is about half of 7.8, or in scientific terms, the first subharmonic of 8 Hz [11]. Therefore, we propose the following method for advantageously benefiting from their finding, using the EM Pulser and the included free Velcro strap fed through the aforementioned belt loops. A similar calculation is proposed on the next page for their long-term memory (LTM) improvement, in this reprint from the IRI EM Pulser Manual.

This examination of the recently discovered health benefits of fast-rise-time pulsed electromagnetic fields would not be complete without a literature review as well. The amazing and attractive features of electromedicine are the complete lack of side effects or contraindications, with the exception of the usual warning concerning anyone with a pacemaker, which normally has a sensitive electronic circuit. – Ed. Note

• Cardioprotection from Stress Conditions by Weak Magnetic Fields in the Schumann Resonance Band Nature Scientific Reports, (2019) 9:1645 “We show that applying 7.8Hz, 90nT magnetic fields (MF) causes a gradual decrease in the spontaneous calcium transients’ amplitude…. However, the effect is frequency dependent; the described changes occurred only in the 7.6–8Hz range…We show that the Schumann Resonance field-induced reduction in Creatine Kinase release is associated with a stress response process and has a protective character.”

• Long-Term Study of Heart Rate Variability Responses to Changes in the Solar and Geomagnetic Environment Nature Scientific Reports, (2018) 8:2663 “Overall, the study confirms that daily Autonomic Nervous System activity responds to changes in geomagnetic and solar activity during periods of normal undisturbed activity and it is initiated at different times after the changes in the various environmental factors and persist over varying time periods….Increase in cosmic rays, solar radio flux, and Schumann resonance power was all associated with increased HRV and parasympathetic activity”

• Does Schumann Resonance Affect our Blood Pressure? Biomedicine & Pharmacotherapy, Volume 59, Supplement 1, October 2005, Pages S10-S14 “Disease-Related Illnesses [were] negatively associated with Blood Pressure Reactivity to Schumann Resonance (BPR-SR)…suggesting a better health status for those who showed lower BP on enhanced SR days. Males showed higher BPR-SR…than females (P=0.004–0.016).”

• Does Exposure to Extremely Low-Frequency Magnetic Fields Produce Functional Changes in Human Brain? Basic Neurosciences, Genetics and Immunology, Feb. 3, 2009 “Behavioral and neurophysiological changes have been reported after exposure to extremely low frequency magnetic fields (ELF-MF) both in animals and in humans… The increase in paired-pulse facilitation… suggests that PEMFs exposure may produce an enhancement in cortical excitatory neurotransmission. This study suggests that PEMFs may produce functional changes in human brain.”

• Electromagnetic Forces and Life Processes Technology Review, December 1972, Robert O. Becker (author of The Body Electric) “The concept that electromagnetic forces might have any effect upon living organisms-other than the thermal effect due to Joule heating was for many years rejected by the organized biomedical community. But under the weight of experimental evidence this attitude is changing; indeed, the medical community is now expressing considerable interest in the possible therapeutic effects of direct application of small amounts of electrical energy.”

• Long-Lasting, Dissociable Improvements in Working Memory and Long-Term Memory in Older Adults with Repetitive Neuromodulation Nature Neuroscience | VOL 25 | September 2022

| 1237–1246 | www.nature.com/natureneuroscience “The development of technologies to protect or enhance memory in older people is an enduring goal of translational medicine. Here we describe repetitive (4-day) transcranial alternating current stimulation (tACS) protocols for the selective, sustainable enhancement of auditory–verbal working memory and long-term memory in 65–88-year-old people.”

• Magnetic Therapy Alzheimer’s Pulsed Electromagnetic Field Therapy Pemf Bibliography Magnetic Field Enhancement, Transcranial Magnetic Stimulation, 8/14/2019, p. 1-16 https:// earthpulse.net/magnetic-therapy-alzheimers/.

Huang, Mei-Yu, May-Hua Liao, Yang-Kao Wang, Yung-Sheng Huang, Hsiao-Chuan Wen, Am J Chin Med, Effect of lavender essential oil (LEO) on LPS-stimulated inflammation acting to increase HSP70 expression that inhibited LPS-induced inflammatory effect. 2012;40(4):845-59. doi: 10.1142/S0192415X12500632.

Moghadamtousi, Soheil Zorofchian, Elham Rouhollahi , Maryam Hajrezaie , Hamed Karimian , Mahmood Ameen Abdulla , Habsah Abdul Kadir, Annona muricata leaves accelerate wound healing in rats via involvement of HSP70 and antioxidant defence, Int J Surg, . 2015 Jun;18:110-7. doi: 10.1016/j.ijsu.2015.03.026. Epub 2015 Apr 18.

Galli, Rachael, Donna F Bielinski, Aleksandra Szprengiel, Barbara Shukitt-Hale, James A Joseph, Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection, Neurobiol Aging . 2006 Feb;27(2):344-50. doi: 10.1016/j. neurobiolaging.2005.01.017.

Han, Soyoung , Jong-Ryoul Choi, Ki Soon Shin, Shin Jung Kang, Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice, Brain Res. 2012 Nov 5; 1483:112-7. doi: 10.1016/j.brainres.2012.09.022. Epub 2012 Sep 19.

Shen SQ, Zhang Y, Xiang JJ, Xiong CL. Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzymes. World J Gastroenterol. 2007;13(13):1953-1961. doi:10.3748/wjg.v13.i13.1953

Menendez JA, Joven J, Aragonès G, et al., Xenohormetic and antiaging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents. Cell Cycle. 2013;12(4):555-578. doi:10.4161/cc.23756

Putics A, Vödrös D, Malavolta M, Mocchegiani E, Csermely P, Soti C, Zinc supplementation boosts the stress response in the elderly: HSP70 status is linked to zinc availability in peripheral lymphocytes. Experimental Gerontology, 14 Jan 2008, 43(5):452-461, DOI: 10.1016/j.exger.2008.01.002 PMID: 18304769

Zhang, Ying, et al., Molle, W. V., Wielockx, B., Mahieu, T., Takada, M., Taniguchi, T., Sekikawa, K., & Libert, C. (2002). HSP70 Protects against TNF-Induced Lethal Inflammatory Shock. Immunity, 16(5), 685- 695. Retrieved 1 2, 2021, from https://cell.com/immunity/fulltext/ s1074-7613(02)00310-2

Mosser, D. D., Caron, A. W., Bourget, L., Meriin, A. B., Sherman, M. Y., Morimoto, R. I., & Massie, B. (2000). The Chaperone Function of HSP70 Is Required for Protection against Stress-Induced Apoptosis. Molecular and Cellular Biology, 20(19), 7146-7159. Retrieved 1 2, 2021, from http://groups.molbiosci.northwestern.edu/morimoto/ research/publications/mossermcb.pdf

Senf, S. M., Dodd, S. L., McClung, J. M., & Judge, A. R. (2008). HSP70 overexpression inhibits NF-κB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy. The FASEB Journal, 22(11), 3836-3845. Retrieved 1 2, 2021, from https://ncbi.nlm.nih.gov/pmc/ articles/pmc6137947

Tidwell, J. L., Houenou, L. J., & Tytell, M. (2004). Administration of HSP70 in vivo inhibits motor and sensory neuron degeneration. Cell Stress & Chaperones, 9(1), 88-98. Retrieved 1 2, 2021, from https:// ncbi.nlm.nih.gov/pmc/articles/pmc1065310

Turturici, G., Sconzo, G., & Geraci, F. (2011). HSP70 and Its Molecular Role in Nervous System Diseases. Biochemistry Research International, 2011, 618127-618127. Retrieved 1 2, 2021, from https://hindawi.com/journals/bri/2011/618127

Zhang, e. a. (n.d.). HSF1-Dependent Upregulation of HSP70 by Sulfhydryl-Reactive Inducers of the KEAP1/NRF2/ARE Pathway. https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pub med&retmode=ref&cmd=prlinks&id=22118669.

1. Valone Thomas F (2024) How Energy Medicine will Save Health Care. Amer J of Biomedical Sci & Res 21(6).
2. (2023) Bio-Magnetic Device May Enhance Mammalian Tissue Repair. issue of Tech Briefs Magazine 47(6).
3. (2022) Noninvasive Therapy for Cartilage Regeneration. NASA Tech Briefs Johnson Space Center.
4. Thomas J Goodwin, Physiological and Molecular Genetic Effects of Time-Varying Electromagnetic Fields on Human Neuronal Cells. Johnson Space Center, NASA/TP-2003-212054.
5. Streitweiser, Andrew, Clayton Heathcock, Introduction to Organic Chemistry (2^nd)., pp. 104-105
6. Puya Yazdi. https://selfhacked.com/blog/heat-shock-proteins-HSP70-increase-decrease/.
7. Elhalel G, C Price, D Fixler, A Shainberg (2019) Cardioprotection from stress conditions by weak magnetic fields in the Schumann Resonance band. Nature Scientific Reports 9: 1645.
8. Wilson Clare (2021) Red light therapy could improve eyesight that has declined with age. New Scientist, p. 16.
9. Thomas J Goodwin (2011) Lynden B Johnson Space Center, Chief Investigator, Pulsed Electro Magnetic Field (PEMF) Four Year Study by NASA. NASA 4-year collaborative study on the efficacy of electromagnetic fields to stimulate growth and repair in mammalian tissues.
10. Bio-Magnetic Device to Enhance Mammalian Tissue Repair. Also see NASA Tech Briefs.
11. Grover Shrey, Wen Wen, Vighnesh Viswanathan, Christopher T Gill, Robert M G Reinhart, et al. (2022) Long-lasting, dissociable improvements in working memory and long-term memory in older adults with repetitive neuromodulation. Nature Neuroscience, pp. 1237-1246.