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Taurine + Caffeine Combination and Heart Rate Variability (Including Stress Index) in an Elderly Man (61 Years Old) Volume 49- Issue 4

Ivan Domuschiev*

  • Endocrinologist Multiprofile Transport Hospital, Department of Internal Diseases Plovdiv City, Bulgaria

Received: March 20, 2023;   Published: April 10, 2023

*Corresponding author: Ivan Domuschiev, Endocrinologist Multiprofile Transport Hospital, Department of Internal Diseases Plovdiv City, Bulgaria

DOI: 10.26717/BJSTR.2023.49.007832

Abstract PDF

Introduction

The measurement of heart rate variability is the only accurate method for quantifying the function of the autonomic nervous system and its response to stress.Taurine is an amino acid that had been forgotten. But in recent years, its «renaissance» has occurred again. [1] This substance is involved in a number of physiological processes and has a beneficial effect on the muscles, eyes, nervous system and other organs and systems.

Taurine is included in the composition of various energy drinks. It is also used in bodybuilding.Caffeine is one of the most well-known psychostimulants. Coffee is the most commonly used invigorating drink in the world. There are numerous scientific studies on the physiological effects of caffeine. [2-5] It is also present in a number of energy drinks and is used in sports and fitness. The combination of taurine with caffeine is very often used to energize the human body.In this line of thought, the study of the effect of the combination «Taurine + Caffeine» on heart rate variability is relevant. Moreover, the combination of these two substances and its effect on the autonomic nervous system in elderly people over 60 have been insufficiently studied.

Material

We investigated a 61-year-old man in this study. [6-8] He is 178 cm tall, weighs 75 kg and has a BMI of 24.

Method

We used a chest belt «Polar H10» (with BLE Bluetooth transmission of heart signals) to record heart activity. We made a short term measurement (3 min.) of HRV parameters. The obtained data were analyzed with «Kubios HRV» software.

The Design of this Study

First, we measured HRV-parameters in the morning at 8 o’clock immediately after waking up from sleep under basal conditions (at complete rest, in a supine position, at optimal room temperature and complete silence) (Figures 1-3) We carried out the second measurement of the same parameters for 1 hour. 30 min after intake of 1 capsule (500 mg) Taurine (when it is the peak of the effect of taurine in the body), combined with the consumption of 1 cup of instant coffee (Figures 1A-3A). In this way, we can compare the data from the two measurements of HRV-parameters and see what is the effect of this combination on the autonomic nervous system, its sympatho-vagal balance and the stress index.

Figure 1 A. Under basal conditions before intake of Taurine+Caffeine. B. 1 hour 30 minutes after intake of Taurine + Caffeine.

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Figure 2 A. Under basal conditions before intake of Taurine+Caffeine. B. 1 hour 30 minutes after intake of Taurine + Caffeine.

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Figure 3A A. Under basal conditions before intake of Taurine+Caffeine. B. 1 hour 30 minutes after intake of Taurine + Caffeine.

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Results

Our obtained data for HRV-parameters from both measurements are presented in (Figures 1-3 and 1A,2A,3A).

Discussion

From the available results it is clear that after intake of taurine + caffeine combination the readiness index slightly decreased from 71% to 65%, the stress index slightly increased from 17.34 to 19.83, and the LF/HF ratio increased (for account of increased sympathetic tone) from 1.01 to 2.16. SDNN slightly decreased, and Poincaré SD1 also decreased, due to an increase of the sympathetic tone [9-11].

Conclusion

The intake of the combination «Taurine + Caffeine» leads to a slight decrease (deterioration) of HRV- parameters in a 61-year-old man.

References

  1. Schaffer S W, Shimada K, Jong C J, Takashi ItoJunichi Azuma,  et al. (2014) Effect of taurine and potential interactions with caffeine on cardiovascular function. Amino Acids 46: 1147-
  2. Bichler, A, Swenson, A Harris M (2006) A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 31: 471-
  3. D Warburton, E Bersellini, E Sweeney (2001) An evaluation of a caffeinated taurine drink on mood, memory and information processing in healthy volunteers without caffeine abstinence. Psychopharmacology 158: 322-328.
  4. A Scholey D, Kennedy (2004) Cognitive and physiological effects of an “energy drink”: an evaluation of the whole drink and of glucose, caffeine and herbal flavoring fractions. Psychopharmacology 176: 320-330.
  5. L Ryan, C Hatfield M, Hofstetter (2002) Caffeine reduces time-of-day effects on memory performance in older adults. Physiol Sci 13: 68-71.
  6. RJ Huxtable (1992) Physiological actions of taurine. Physiol Rev 72: 101-163.
  7. C Alford, H Cox, R Wescott (2001) The effects of Red Bull Energy Drink on human performance and mood. Amino Acids 21: 139-150.
  8. Seidl R, Peyrl  A, Nicham R, E Hauser (2000) A taurine and caffeine-containing drink stimulates cognitive performance and well-being. Amino Acids 19: 635-642.
  9. Grace E Giles, Caroline R Mahoney, Tad T BrunyГ©, Aaron L Gardony, Holly A Taylor, et al. (2012) Differential cognitive effects of energy drink ingredients Caffeine, taurine, and glucose. Pharmacology Biochemistry and Behavior Volume 102(4) : 569-577.
  10. Ozan M, Buzdagli Y, Eyipinar C D, Baygutalp N K, Yüce N, et al. (2022). Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study. Nutrients 14(20):
  11. (1996) Heart rate variability standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electro-physiology. Circulation 93(5): 1043-1065.