Lourdes Serrano García*
Received: July 24, 2022; Published: August 05, 2022
*Corresponding author: Lourdes Serrano Garcia, University of Medical Sciences of Holguin, Cuba
The analysis of protein expression profile upon diverse conditions in health and disease, was coined as proteomics in the early 90´s. These types of studies led to myriad progress in the field of sports medicine research because the understanding of the proteome modulation in response to exercise, is a cornerstone in achieving a deeper understanding of the molecular mechanisms involved in the complex health-disease process in athletes . In addition, integration of the results of proteomic data with the clinical, biochemical and sports pedagogical indicators will help in the development of personalized recommendations for the effective planning of the athlete training processes. This latter includes the choice of sports specialization, optimization of the training process and assessment of the current functional state of an athlete (such as overtraining) . As is known, sports medicine is a wide medical field that deals with sports related injuries and support and also plays a major role in prevention, recovery, and pain relief . In relation to this young science, it should be noted that, today, the global scientific community is actively working to identify the endogenous molecular factors and processes that can act as personalized predictors of athletic performance .
Among the most recent advances evidenced in the field of
sports medicine, provided by the development of proteomics, the
following can be mentioned:
a. Proteomic tools coupled with mass spectrometry and bioinformatic technologies used in data analysis, responsible to complement the significant number of molecular players and cell pathways included in the pathogenesis of diseases in athletes .
b. The influence of diet and exercise on the anthropometric profile in competitors .
c. The identification of the target proteins of exerciseinduced stress in urine from male athletes, based on twodimensional gel electrophoresis and mass spectrometry procedures. This provides new ideas for further exploring exercise-induced proteinuria .
d. The characterization of acute exercise-induced changes in salivary proteins of street runners, which provides a better understanding of the acute effects of exercise . e. The study of the mechanisms of muscle adaptation, using emerging techniques for dynamic analysis of muscle proteomes .
f. The evaluation of the relationships of proteomics data, athlete-reported illness, athlete training distress, and coaches’ ratings of distress and performance over the course of the competitive season.
In this case it was showed the importance of the immune system in the reaction to internal and external stress in athletes . In Cuba, the learning of the contents related to proteomics in the field of sports health is promoted from professional training in various careers related to the subject, although its realization in most cases is achieved in the postgraduate. In this context, the professional profile of health personnel requires the graduation of an individual who demonstrates a high level of knowledge and pertinent modes of action. In the particular case of the specialty of Medical Microbiology, proteomics is taught from the first year of internship as a subject . The teaching experience of more than eight years of the author of this material in the teaching of this subject, allows ensuring that it offers sufficient theoretical-practical tools to comprehensively address health situations in which this science is involved. The multidisciplinary cathedras of genomic medicine in Cuba, created throughout the university network, have the social commission of promoting professional training in Omics technologies . Numerous advances have been made in the field of biotechnology, public health and molecular biology in the country, thanks to the coordinated work of scientific and academic institutions . In this sense, it is worth mentioning the production of proper drugs and vaccines, which allow the increase of the quality of life of the communities and age groups. However, in the field of sports medicine, there are few works related to the progress of proteomics in this branch. It is evident that this science requires a solid economic investment and a highly trained human resource to achieve good results, and this can become in a real limitation.
The theoretical and technical development of proteomics constitutes nowadays the referential and normative framework of numerous sciences and branches of science. It can be assured that the transversality and diversification of proteomics has become in an unavoidable path in finding accurate and precise solutions. In the field of sports medicine, there are important advances aimed, regarding to the improvement of teaching-learning processes, which allows the increases in quality of life of coaches and athletes. In this sense, proteomics is considered as an essential science for the revitalization of preventive actions, treatment, and rehabilitation of athletes.
Author (Lourdes Serrano) offers sincerest acknowledges to the Financial and Editorial offices of the Biomedical Journal of Scientific & Technical Research (BJSTR) for the complete financing of this paper..
The author has declared that no competing interest exists.