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Extraction and Analysis of Bioactive Compounds from Dipsacus Fullonum and Galium Verum for Lyme Borreliosis Treatment

Volume 11 - Issue 4

Maria Kuhtinskaja and Merike Vaher*

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    • Institute of Chemistry and Biotechnology, Tallinn University of Technology, Estonia
    • *Corresponding author: Merike Vaher, Institute of Chemistry and Biotechnology, Estonia

Received: November 22, 2018;   Published: November 29, 2018

DOI: 10.26717/BJSTR.2018.11.002121

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Four different methods for the extraction of bioactive compounds from the two medicinal plants were compared. Based on qualitative analysis and comparison of chromatograms, all extracts can be characterized by a high content of polyphenols and iridoids. The identification of major bioactive compounds in both plant extracts were carried out using HPLC-MS analysis. More than fifteen different constituents were identified. The highest amount of iridoid glucosides were observed in Dipsacus samples.

Keywords : Bioactive Compounds, Dipsacus Fullonum, Galium Verum, HPLC-MS, Extraction, Lyme Borreliosis

Abbreviations : HWE - Hot Water Extraction; PHWE - Pressurized Hot Water Extraction

Introduction| Materials and Methods| Results and Discussion| Conclusion| Acknowledgement| References|