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Trends in Pharmacogenetics

Volume 11 - Issue 2

Shweta S Joshi and Husayn Ahmed P*

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    • National Centre for Biological Sciences, India
    • *Corresponding author: Husayn Ahmed P, National Centre for Biological Sciences, India

Received: November 16, 2018;   Published: November 21, 2018

DOI: 10.26717/BJSTR.2018.11.002073

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Abstract

Since the initial studies in the 1950s, the field of pharmacogenetics has shown a lot of promise. The advent of high-throughput technology and next-generation sequencing has only added to the development of this field. Amidst several challenges like the lack of a comprehensive genomic database and varied prescription practices, pharmacogenetics has immense potential from the personalized medicine, novel biomarker discovery and drug development perspective in a genetically diverse population like India.

Keywords : EMEA: European Agency For Evaluation of Medicinal Products, ADRS: Adverse Drug Reactions, PD: Pharmacodynamics, PK: Pharmacokinetics, CPIC: Clinical Pharmacogenetics Implementation Consortium

Introduction| Pharmacogenetics in a Nutshell and its History| Need for Pharmacogenetics in the Indian Context| Potential Applications and Challenges| Conclusion References|