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Research ArticleOpen Access

Oral Candida Albicans Colonization in Dental Prosthesis Patients and Individuals with Natural Teeth, Sana’a City, Yemen

Volume 11 - Issue 2

Omar Ahmed Esma’il Al-Dossary and Hassan A Al-Shamahy*

  • Author Information Open or Close
    • Medical Microbiology and Clinical Immunology, Faculty of Medicine and Health Sciences, Sana’a University, Yemen
    • *Corresponding author: Hassan A Al-Shamahy, Medical Microbiology and Clinical Immunology, Faculty of Medicine and Heath Sciences, Sana’a University, Yemen

Received: November 10, 2018;   Published: November 20, 2018

DOI: 10.26717/BJSTR.2018.11.002072

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Background: The capability of the Candida albicans Candida (CAC) to colonize surfaces can be signify as a risk factor for oral infection, thus, denture wearing approves of a stable factor that can affect oral health status.

Objectives: This study investigated risk factors associated with progress to Candida-related denture colonization in dental prosthesis comparing to individuals with natural teeth.

Methods: A total of 208 subjects were studied: 104 denture wearers and 104 non-denture wearers, matched by age and sex, comprised the experimental and control groups, respectively. Each subject was directed to perform oral rinsing using a phosphate-buffered saline solution, which was expectorated and processed for the recovery of Candida species on Sabouraud’s dextrose agar. Isolates were identifying by culturing on chromogenic Candida agar and noting species-specific colony characteristics.

Results: There was a significant oral Candida albicans colonization rate (OCAC) among denture wearers equaled to 61.5% comparing with 33.6% among non-denture wearers with a significant association (OR) of OCAC =3.2, and PV<0.001. Plus, there were significant association between OCAC and male denture wearers (OR= 2.8, PV<0.001), increase of patient age (≥65 years OR=2.2, PV=0.01) and wearing complete denture (OR=2.6, PV=0.02). Conclusions: Based on the results of this study ability of OCAC were greater in denture wearers than non-denture wearers, also greater risk of OCAC found with males, older ages and wearing complete denture. In addition, the study results are important for understanding OCAC in dentures and development strategies to reduce or eliminate OCAC in denture wearers.

Keywords : Oral C.albicans colonization (OCAC); Denture; Natural Teeth; Risk Factors; Yemen

Introduction| Subjects and Laboratory Methods| Data Analysis| Ethical Approval| Result| Discussion| Conclusion| References|