*Corresponding author:David Hevia, Research and Development Department, Morphology and Cell Biology Department, Redox Biology Group, Oviedo, Spain
Received: November 16, 2018; Published: November 20, 2018
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Total Antioxidant Capacity or TAC is an indicator of the sample ability to scavenge free radicals despite its complex composition. It has been measured in biological fluids as an inverse biomarker of oxidative stress, which has been related to disease. Classical spectrophotometric methods present some limitations including sample pretreatment required leading to long assay procedures, native pH alteration, low stability of some reagents, high detection limits, low sensitivity and sample’s colour interference. Various electrochemical techniques have raised as more precise alternatives that overcome most of the limitations in classical methodologies and have been gaining popularity specially for food and beverage analysis. In this mini review, an electrochemical measurement of antioxidant capacity with applications in vitro and in vivo is presented.
Keywords : Total Antioxidant Capacity; Electrochemical; Voltammetry; Biological samples; Oxidative stress
Abbreviations : TAC: Total Antioxidant Capacity; TEAC: Trolox Equivalent Antioxidant Capacity, GAE: Gallic Acid Equivalents; CEAC: Vitamin C Equivalents Antioxidant CapacityIntroduction| Conclusion| Acknowledgement| References|