+1 (502) 904-2126   One Westbrook Corporate Center, Suite 300, Westchester, IL 60154, USA   Site Map
ISSN: 2574 -1241

Impact Factor : 0.548

  Submit Manuscript

Mini ReviewOpen Access

Fast and Accurate Electrochemical Measurement of Total Antioxidant Capacity as an Alternative to Spectrophotometrical Methods

Volume 11 - Issue 2

Susana Rey1, Esther Gómez1, Henar Muñoz-Cimadevilla1 and David Hevia*1,2

  • Author Information Open or Close
    • 1Research and Development Department, Spain
    • 2Morphology and Cell Biology Department, Redox Biology Group, Spain
    • *Corresponding author: David Hevia, Research and Development Department, Morphology and Cell Biology Department, Redox Biology Group, Oviedo, Spain

Received: November 16, 2018;   Published: November 20, 2018

DOI: 10.26717/BJSTR.2018.11.002069

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF


Total Antioxidant Capacity or TAC is an indicator of the sample ability to scavenge free radicals despite its complex composition. It has been measured in biological fluids as an inverse biomarker of oxidative stress, which has been related to disease. Classical spectrophotometric methods present some limitations including sample pretreatment required leading to long assay procedures, native pH alteration, low stability of some reagents, high detection limits, low sensitivity and sample’s colour interference. Various electrochemical techniques have raised as more precise alternatives that overcome most of the limitations in classical methodologies and have been gaining popularity specially for food and beverage analysis. In this mini review, an electrochemical measurement of antioxidant capacity with applications in vitro and in vivo is presented.

Keywords : Total Antioxidant Capacity; Electrochemical; Voltammetry; Biological samples; Oxidative stress

Abbreviations : TAC: Total Antioxidant Capacity; TEAC: Trolox Equivalent Antioxidant Capacity, GAE: Gallic Acid Equivalents; CEAC: Vitamin C Equivalents Antioxidant Capacity

Introduction| Conclusion| Acknowledgement| References|