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Research ArticleOpen Access

Crispr/Cas9 System - A Revolution in Gene Editing

Volume 10 - Issue 1

Nikolai Adamov1, Volodia Georgiev2 and Teodora Daneva*3

  • Author Information Open or Close
    • 1 Faculty of Chemistry and Pharmacy, Sofia University, Bulgaria
    • 2 Manhattanville College, USA
    • 3 Bulgarian Academy of Sciences, Sofia University, Bulgaria
    • *Corresponding author: Teodora Daneva, Institute of Biology and Immunology of Reproduction, Bulgarian Academy of Sciences, Sofia, Bulgaria

Received:October 03, 2018;   Published: October 16, 2018

DOI: 10.26717/BJSTR.2018.10.001902

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Abstract

Abbreviations : CRISPR: Clustered Regularly-Interspaced Short Palindromic Repeats; RM: Restriction-Modification; PAM: Proto Spacer Adjacent Motif; SCA: Sickle Cell Anemy; HDR: Homology Directed Repair; DMD: Duchenne Muscular Dystrophy; PTP: Protein Tyrosine Phosphatases; ER: Endoplasmic Reticulum; AAV: Adeno Associated Virus; IPSC: Induced Pluripotent Stem Cell

Abbreviations: | Introduction| History and Origin| How CRISPR Works| Application| Ethical Issues| Conclusion| References|