Crispr/Cas9 System - A Revolution in Gene Editing

Nikolai Adamov; Volodia Georgiev; Teodora Daneva

doi:10.26717/BJSTR.2018.10.001902

Research ArticleOpen Access

Crispr/Cas9 System - A Revolution in Gene Editing

Volume 10 - Issue 1

**Nikolai Adamov¹, Volodia Georgiev² and Teodora Daneva*³**

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- ¹ Faculty of Chemistry and Pharmacy, Sofia University, Bulgaria
- ² Manhattanville College, USA
- ³ Bulgarian Academy of Sciences, Sofia University, Bulgaria

Received:October 03, 2018; Published: October 16, 2018

DOI: 10.26717/BJSTR.2018.10.001902

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Abstract

Abbreviations : CRISPR: Clustered Regularly-Interspaced Short Palindromic Repeats; RM: Restriction-Modification; PAM: Proto Spacer Adjacent Motif; SCA: Sickle Cell Anemy; HDR: Homology Directed Repair; DMD: Duchenne Muscular Dystrophy; PTP: Protein Tyrosine Phosphatases; ER: Endoplasmic Reticulum; AAV: Adeno Associated Virus; IPSC: Induced Pluripotent Stem Cell