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Smart Cyclodextrin-Based Drug Delivery Systems: Stimuli-Responsiveness and Controlled Release

Volume 9 - Issue 5

Shohreh Peimanfard1,2, Fabrizio Caldera*2, Alberto Rubin Pedrazzo2 and Nilesh Kumar Dhakar2

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    • 1Department of Biotechnology, University of Isfahan, Iran
    • 2Department of Chemistry, University of Torino, Italy

    *Corresponding author: Fabrizio Caldera, Department of Chemistry, University of Torino, Torino, Italy

Received: September 27, 2018;   Published: October 09, 2018

DOI: 10.26717/BJSTR.2018.09.001850

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Abstract

Cyclodextrins (CDs), a family of macrocyclic oligosaccharides, are well known as drug carriers due to their specific structures and properties. Their adequate size and truncated cone-shaped architecture with inner slightly hydrophobic cavity and outer hydrophilic surface provide suitable space for interaction with many types of organic and inorganic compounds, including ions, proteins and oligonucleotides.

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