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ISSN: 2574 -1241
ISSN: 2574 -1241
Received: August 01, 2018; Published: August 14, 2018
DOI: 10.26717/BJSTR.2018.08.001580
The biocompatibility of calcium phosphates is well known in the scientific community and they can be used as a replacing or filling material in cases that the bone was severely broken, demineralised by osteoporosis or bacterial activity and after removal of tumours. This work showed different synthesis, characterizations and applications of tricalcium phosphate (TCP) as a bone substitute. It was observed that the crystalline phase, synthesis method, porosity, grain size and biodegradability of TCP can improve the biocompatibility and osseointegration of biomaterials. In this review, TCP showed superior characteristics than hydroxyapatite. In conclusion, TCP is a promising material and further researches are needed to enhance the production and use as a bone substitute.
Keywords: Tricalcium Phosphate; TCP; Bone Substitute; Biomaterial; Hydroxyapatite
Abbrevations: TCP: Tricalcium Phosphate; HAP: Hydroxyapatite; XRD: X-Ray Diffraction; FTIR: Fourier Transform Infrared Spectroscopy; ASAP: Accelerated Surface Area and Porosimetry; SEM: Scanning Electron Microscopy
Abstract | Introduction | Materials and Methods | Discussion | Acknowledgment | References |
International Association of Landscape Archaeology, Czech Glass Society, Czech Republic
Department of Chemistry, Semenov Institute of Chemical Physics, USSR Academy of Sciences, Moscow, Russia
Pharmaco-kinetics, dynamics and Drug Metabolism, Touro College of Pharmacy, USA
Professor of Nuclear Medicine, Faculty of Medicine and Surgery, University of Milan, Milan, Italy
Associate Professor at Department of Breast and Thyorid Surgey, Chongqing General Hospital, China
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