*Corresponding author:László Hodinka, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary H-1023 Budapest Frankel Leó u. 25-29
Received: July 17, 2018; Published: July 25, 2018
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Sarcopenia is the progressive involution of musculature, with a decrease of power and with limitation of physical and cognitive functions, including isolation, loss of independence and impairment of the quality of life. It is a gerontology syndrome, a component of age-related frailty. Because of the dismobility there is a hazard of falls and fractures with a significant mortality risk. This article reviews the relation of sarcopenia to aging, definition and epidemiology and pathophysiology of sarcopenia with publications and recommendations for screening, diagnostic tools and therapeutic modalities.
Abbreviations: BMI: body mass index; EuroQoL-5D, EQ-5D: European Quality of Life 5 Dimension Questionnaire; EWGSOP: European Working Group on Sarcopenia in Older People; HRQoL: Health Related Quality of Life; SarQoL: Sarcopenia Quality of Life Questionnaire; SF-36: Rand Corporation Short Form Questionnaire 36 question version SMM… skeletal muscle mass; and skeletal muscle mass index, SMI: skeletal muscle mass index; SPPB: Short Physical Performance Battery.