*Corresponding author:Xin Li, Department of Emergency, the People’s Hospital of Linzhi, Xizang, 860000, P.R. China
Received: July 12, 2018; Published: July 23, 2018
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Bladder cancer is one of the most common malignant tumors in the human body. At this stage, there is no significant progress in treatment. Therefore, early diagnosis of bladder cancer is particularly important. At present, the urine cytology screening, cystoscopy and pathological analysis are the most effective method for bladder cancer diagnosis. Due to the low specificity of urine exfoliated cells and cystoscopy is an invasive examination which is difficult for many patients to accept, there is an urgent need to find biomarkers of bladder cancer and to elucidate the mechanism of progression of bladder cancer for later treatment. Recently, some scholars have focused their attention on exosomes, which are a kind of nano-sized vesicle structure secreted by cells. They are distributed in various body fluids such as blood, saliva and urine. As an important class of intercellular communication molecules, exosomes contain a variety of biologically active components, which can play a regulatory role in the human body in a variety of ways. This paper is mainly about the introduction of bladder cancer exosomes.
Keywords: Bladder Cancer; Exosomes; Biomarker
Abbreviations: HDL: High-Density Lipoproteins; RISC: RNA-Induced Silencing Complex